The first draft:

The second draft: spacing, colors, and (ahh!) a bit of white out not satisfactory.

Trying again, fixing spacing, and laying out different colors in this one:

And this one:

Drafting a border...

Based on this:
(A page from the 14th Cen. Metz Potifical which actually was intended to be pigmented)

Putting the border on the lettering. Not so happy with it.

Drafting another border:

Inspired by this:
(Page from Chaucer's Romaunt of the Rose, Circa 1440)

And the "S" curves in this:

Also referencing the rod on Asclepius, a symbol of medicine.